12 results
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Female:Male 9:1 • Common ... intralobular bile ducts causes ... failure PBC Signs ... asymptomatic • Pruritus ... Examination: • Skin
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
eosinophilia (common ... organ-specific signs ... symptoms (eg, skin ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
sweats, bleeding • Pruritis ... Neutrophils • Immature/Myeloblasts ... CLL -> Invade Skin ... #Hematology #Oncology ... #Diagnosis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
disease or more commonly ... GPA causes disease ... associated with pruritus ... reticularis Differential ... #rheumatology
Common Dermatological Conditions - Distribution and Morphology
 • Acne vulgaris - Face, upper back, chest -
Common Dermatological ... associated with signs ... • Herpes simplex ... #rash #differential ... #diagnosis #skin
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
of age • Most common ... Behcet disease) Differential ... tears, Ischemia, Leukemia ... #management #signs ... #symptoms #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... Drug Associated (Commonly ... Associated: (± 100 % Commonly ... purpura: strong sign ... #diagnosis #rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
definition: Most common ... systemic sx + signs ... very remarkable w/differential ... required due to skip ... them, but urgent rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... purpura: Strong sign ... Nodosa: • PAN most commonly ... tract, and often causes ... #Diagnosis #Rheumatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... Most common cytopenia ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology