6 results
diagnosis chronic cll cvid differential erythematosus gammopathies globulin immunodeficiency immunology lupus lymphocytic mgus monoclonal multiplemyeloma proteingap sle variable workup
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Lymphoma or other cancers ... hemolytic anemia) • Systemic ... DDX - Other causes ... • Burns • Protein-losing ... #immunology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
- Summary Cancer ... rendering the immune system ... Epidemiology: • Most common ... diagnosis #workup #oncology ... #hematology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Look for gamma gap ... (total protein ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... Neutrophils • Immature/Myeloblasts ... lymphoid organs When Cancer ... Agranulocytosis • Hypogammaglobulinemia ... #Hematology #Oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Gap (Total Protein ... changes (POEMS syndrome ... gastric tumors • Hematology ... Comment on type ... differential #diagnosis #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
pancreatitis, protein-losing ... Kidney disease common ... Hodgkin lymphoma and leukemia ... • Lung cancer ... Erythematosus #Diagnosis #Rheumatology
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