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White Blood Cell Maturation Chart

#Pathology #WBC #Maturation #Lineage #Chart #Leukocyte #Myeloid #Myeloblast #Lymphocyte
Maturation Chart #Pathology ... Leukocyte #Myeloid #Myeloblast
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
large, immature myeloblasts ... acute myelogenous leukemia
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... , CLL Acute leukemias ... Chronic leukemia ... Lymphoblastic Leukemia ... Neutrophils • Immature/Myeloblasts
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Plasma cell leukemia ... primary plasma cell leukemia ... #PlasmaCell #leukemia ... Smear #Hematology #Pathology
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
cells within the myeloblast ... Leukemoid reaction ... Leukemias or myeloproliferative ... Leukemoid Reaction ... D/D leukemia: increases
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
T-prolymphocytic leukemia ... Acute Myeloid Leukemia ... Smear #Peripheral #Pathology
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... promyelocytic #leukemia ... #APL #APML #Pathology
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
acute myeloid leukemia ... Clinical #Hematology #Pathology
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia
Clinical
 - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
T-LGL leukemia - ... Granular Lymphocytic Leukemia ... Predominantly leukemic ... #Lymphocytic #Leukemia ... #hemepath #pathology
Acute and Chronic Leukemia Subtypes - Classification

Remember that AML is the most common acute leukemia among
Acute and Chronic Leukemia ... most common acute leukemia ... common chronic leukemia ... #Leukemia #Subtypes