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diagnosis differential hematology causes clinical oncology management algorithm microscopy pathology blood dermatology bloodsmear path treatment anemia auer chronic lactate rods
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... Neutrophils • Immature/Myeloblasts ... develop leukostasis syndrome ... • Peripheral smear ... • Tumor lysis syndrome
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
large, immature myeloblasts ... acute myelogenous leukemia ... BloodSmear #Blood #Smear
Plasmacytomas and Plasma-Cell Leukemia - Physical examination revealed multiple exophytic subcutaneous lesions involving the arms and
and Plasma-Cell Leukemia ... peripheral-blood smear ... Plasmacytomas #PlasmaCell #Leukemia ... #Smear #NEJM
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Plasma cell leukemia ... primary plasma cell leukemia ... #PlasmaCell #leukemia ... formation #Clinical #Smear
Prolymphocytes In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML). 🔬Tumor
T-prolymphocytic leukemia ... Acute Myeloid Leukemia ... Prolymphocytes #Smear
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... promyelocytic #leukemia ... Hematology #Clinical #Smear
Hypersegmented neutrophil in a case of acute myeloid leukemia. Dysplastic neutrophils are typically hypolobated but can be
acute myeloid leukemia ... Hematology #Pathology #Smear
Evaluation of Leukocytosis: The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages. Include
cells within the myeloblast ... Leukemoid reaction ... Leukemias or myeloproliferative ... Leukemoid Reaction ... D/D leukemia: increases
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... • Most common leukemia ... • Peripheral smear ... • Richter’s Syndrome ... • Sezary syndrome
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytic leukemia ... peripheral blood smear ... acute myeloid leukemia ... mixed lineage leukemia ... BloodSmear #Blood #Smear
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