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diagnosis differential classification rheumatology algorithm anemia cbc chronic crisis dyspnea fatigue hyperpnea hypertension infections infectiousdiseases leukemia management mentzerindex mycobacteria nephrology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... • Blasts > 10% leukocytes ... Neutrophils • Immature/Myeloblasts ... - infiltrates (anemia ... #Leukemia #Hematology
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
- Tamponade Pulmonary ... Vasculature: - PE - Pulmonary ... Transverse myelitis • Hematology ... : - Anemia • ... #pulmonary
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview ... peripheral blood leukocytes ... on the left Myeloblast ... Degree of bandemia ... neutrophil #WBC #CBC #hematology
Tachypnea - Differential Diagnosis Framework Definitions • Tachypnea: Respiratory rate > 20/min, shallow breathing in adults •
deep breathing Pulmonary ... Tachypnea: • Pulmonary ... effusion/Tamponade Hematologic ... : • Anemia ... Differential #Diagnosis #pulmonary
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... Pancytopenia is a hematologic ... 150,000 per mcL, and leukocytes ... majority of the leukocytes ... These causes could
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Neoplastic / Hematologic ... • Anemia • ... Chronic Obstructive Pulmonary ... Diagnosis #Algorithm #causes
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Classification of Pulmonary ... Pulmonary arterial ... Chronic hemolytic anemia ... multifactorial mechanisms Hematologic ... #Differential #Causes
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
decrease in most cases ... result in severe anemia ... immune hemolytic anemia ... a left shift Urinalysis ... Diagnosis #Workup #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
progressing GN • New pulmonary ... glomerulonephritis and/or pulmonary ... tract, and often causes ... arthritis, obstructive pulmonary ... , and SLE) • Urinalysis
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Illnesses: • Pulmonary ... complicate MAC pulmonary ... Hematologic malignancy ... Bone Marrow - Anemia
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