7 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... Polyangiitis (GPA ... GPA causes disease ... vasculitis #Dermatologic ... #dermatology #rash
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Disease Classification ... fibromyalgia) • Infections ... lupus erythematosus ... #Lupus #Erythematosus
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Feature A Monoclonal Protein ... Lymphoma (HCV) • CLL ... to cold IgG • Lupus ... Pseudohyponatremia • ↓anion gap ... Paraproteinemias #Hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Gap (Total Protein ... gammopathy, and skin ... gastric tumors • Hematology ... #differential # ... diagnosis #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
> PR3 60% • GPA ... mucositis - Rash ... lupus erythematosus ... • ANCA (Dx: GPA ... #classification
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
: Erythematous nodules ... , mucositis • Rash ... with elevated protein ... MPO > PR3 60/ GPA ... tract, and often causes
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Nontuberculous Mycobacteria ... status NTM Cause ... disease, alcohol, cancer ... #differential # ... diagnosis #infectiousdiseases