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diagnosis hematology vasculitis globulin joint lupus pain polyangiitis protein proteingap systemic vasculitides
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... Maculopapular rash ... • Goodpasture syndrome ... #dermatology #rash
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Joint Pain Rash ... Sarcoidosis • GPA ... Antiphospholipid-antibody syndrome ... #dermatology ... #rashes #differential
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... • Tumor lysis syndrome ... lymphoid organs When Cancer ... -> Invade Skin: ... #Hematology #Oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
evidence of (fatigue, rash ... eruption - Butterfly rash ... rash • Erythematous ... lymphoma • Evans' syndrome ... Shrinking lung syndrome
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Globulin - Protein Gap ... gammopathy, and skin ... changes (POEMS syndrome ... gastric tumors • Hematology ... #diagnosis #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
> PR3 60% • GPA ... Mucocutaneous lymph node syndrome ... mucositis - Rash ... VASCULITIS: • Behçet Syndrome ... • Cogan Syndrome
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Mucocutaneous lymph node syndrome ... , mucositis • Rash ... MPO > PR3 60/ GPA ... vasculitis • Behcet syndrome ... vasculitis • Cogan syndrome
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