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hematology leukemia allergy chronic classification globulin immunology lymphocytic lymphoma management mds monoclonal myelodysplasia myelodysplastic paraproteinemias pathergy protein proteingap syndromes
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... • (Peripheral eosinophilia ... -> Invade Skin: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... Diagnosis: • ... lymphoproliferative disorders ... #workup #oncology ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... • Autoimmune disorders ... Lymphoma Workup ... Immunohistochemical studies (to differentiate ... #oncology #management
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... Episodic angioedema+eosinophilia ... Pseudohyponatremia • ↓anion gap ... #Monoclonal #Differential ... #Diagnosis #Oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... involve one, two, or all ... three myeloid hematopoiesis ... Myelogenous Leukemia (CML ... #hematology #oncology
Pathergy Summary Overview What is pathergy? Pathergy is an exaggerated skin injury occurring after minor trauma such as
syndrome • Chronic myeloid ... leukemia (CML) ... Myeloproliferative disorders ... syndrome • Non-Hodgkin's ... #differential #
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... gammopathy, and skin ... Connective tissue disorders ... #ProteinGap #differential ... #diagnosis #hematology
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