17 results
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Reactive: • Anemia ... Polycythemia Vera • Primary ... Myelofibrosis • Chronic Myeloid ... #Diagnosis #causes ... #Platelets #hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
- Differential ... malignancies • Anemia ... Post-splenectomy Primary ... MF) • Chronic myeloid ... #hematology #secondary
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Causes == Primary ... Skin Lesions == ... renal failure/uremia ... #generalized #dermatology ... Diagnosis #Algorithm #causes
Great Mimickers - SHALLOTS Mnemonic

S- Syphilis - Neurosyphilis, aortitis, gummas... Granulomas can form anywhere! Skin, mucosa,
Skin, mucosa, joints ... dermatitis, dementia, anemia ... A - Amyloid - Amyloid ... dyspnea, ulcers, arthritis ... Mnemonic #Diagnosis #Differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... /Quantity: • Primary ... - Hemolytic anemia ... Vasculopathy #Purpura #Differential
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... Examination: • Skin ... bile ducts Differential ... diagnosis #workup #hepatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... with GCA or as primary ... Primary Angiitis ... tract, and often causes ... #Diagnosis #Rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
very remarkable w/differential ... systemic complaints- anemia ... required due to skip ... identifies 85 to 95% of cases ... Symptoms #Diagnosis #Management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... - infiltrates (anemia ... + distinctive primary ... CLL -> Invade Skin ... #Leukemia #Hematology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Pruritus - No Primary ... Skin Lesion - Differential ... renal failure/uremia ... #generalized #dermatology ... Diagnosis #Algorithm #causes