7 results
diagnosis oncology agglutinin arteritis cold disease gammopathies gammopathy gap giantcell globulin hemolytic management multiplemyeloma paraproteinemias plasmacytoma proteingap significance signs solitary
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
protein level <3 ... No evidence of anemia ... protein level ( ... insufficiency, Anemia ... protein level <
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Multiple Myeloma ... 40 ml/min A - Anemia ... gamma gap (total protein ... #Gammopathies #MGUS ... #diagnosis #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Protein/M Component ... Lymphoma (HCV) • CLL ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... younger pts) Differential ... significance (MGUS ... ), CLL, Myeloma ... #hematology #diagnosis
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... (GCA) Giant cell ... very remarkable w/differential ... systemic complaints- anemia ... in literature (NEJM
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Gammopathy Include: • MGUS ... • Multiple myeloma ... • Plasma cell ... anemia • Other ... Gap #ProteinGap #differential
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
tissue composed of monoclonal ... • No CRAB - no anemia ... + diff • CMP, Ca ... IFE, FLC assay Pathology ... Diagnosis #Workup #Hematology
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