3 results
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Gap (Total Protein ... : • MGUS • Multiple ... myeloma • Waldenstrom ... Thalassemia, Sickle cell anemia ... #differential #
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
younger pts) Differential ... gammopathy of undetermined ... significance (MGUS ... ), CLL, Myeloma ... #anemia #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Protein/M Component ... • Coombs (-) hemolytic ... anemia due to cold ... Paraproteinemias #Hematology ... #Monoclonal #Differential