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diagnosis differential vasculitis cryoglobulinemia cryoglobulins erythematosus gap globulin leukemia lupus mds myelodysplasia myelodysplastic myopathy myositis protein proteingap sle syndromes types
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Symptoms: • Asymptomatic ... associated with autoimmune ... processes: • Systemic ... #diagnosis #rheumatology ... #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
, inflammatory arthritis ... vasculitis, rheumatoid arthritis ... rheumatologic diseases ... Arthritis: • ... limited to: Arthritis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
diseases: - 10% ... arthralgia, and arthritis ... SLE), rheumatoid arthritis ... diagnosis #types #classification ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
arthritis. (± glomerulonephritis ... Glomerulonephritis, arthritis ... mucositis - Rash, arthritis ... Symptoms (Sx) in ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
GCA (Giant Cell Arteritis ... mucositis • Rash, arthritis ... arthritis. ... Glomerulonephritis, arthritis ... Differential #Diagnosis #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... - infiltrates (anemia ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... , or all three myeloid ... Marrow Failure • Chronic ... #diagnosis #hematology ... #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... (RA, Temporal arteritis ... Cirrhosis, ETOH, autoimmune ... gastric tumors • Hematology ... differential #diagnosis #hematology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... • Nonerosive arthritis ... • Conduction system ... statins - probably caused ... Myositis #Myopathy #rheumatology
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