36 results
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
and signs. ... Symptoms: Tiredness ... Carpal timel syndrome ... hypertrophy, Proximal myopathy ... #PhysicalExam #
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
level of muscle weakness ... less systemic symptoms ... heliotrope rash, Shaw sign ... , holster sign, ... anti-synthetase syndrome
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Weakness • Spinal ... Guillain-Barre syndrome ... Mitochondrial myopathy ... #diagnosis #neurology
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Causes of Peripheral ... Lambert-Eaton Myasthenic Syndrome ... • Congenital Myopathy ... #Neurology #Differential ... Diagnosis #Algorithm #Causes
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
80%) - Proximal Weakness ... femoral heads • Myopathy ... (Also caused by ... pathophysiology #signs ... #symptoms #diagnosis
Myoedema in Hypothyroidism on Physical Exam

Hypothyroidism is a clinical syndrome resulting from the production, secretion or
is a clinical syndrome ... characterized by muscle weakness ... reflex hammer, caused ... Hypothyroidism #PhysicalExam ... clinical #video #neurology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
and signs below ... Non-compressive Spinal Cord Causes ... - Radiation myelopathy ... MCTD, Sjogren syndrome ... disorders #diagnosis #neurology
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... Lower motor neuron symptoms ... Upper motor neuron symptoms ... - Radiation myelopathy ... differential #diagnosis #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
• Acute stroke syndromes ... Paraneoplastic syndrome ... Lack of UMN/LMN signs ... Myopathy: ... Differential #Diagnosis #neurology
NINDS Diagnostic Criteria for Guillain Barre Syndrome 
Features Required for Guillain-Barré Syndrome:
 • Progressive muscle weakness
Progression of weakness ... , Mild sensory symptoms ... or signs, Cranial ... nervous system signs ... diagnosis #criteria #neurology