447 results
Myositis and Myopathies
#ESR #CK #Differential diagnosis of myopathy 
#Inflammatory #myopathies	#Dermatomyositis	
#muscle weakness
#Polymyositis	
#Inclusion body myositis
#Polymyalgia rheumatica	
#Fibromyalgia	
#Hypothyroid myopathy	
#Muscle stiffness
#Drug-induced
Myositis and Myopathies ... #Inflammatory ... #myopathies #Dermatomyositis ... #Hypothyroid myopathy ... Statin-induced myopathy
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Idiopathic Inflammatory ... Myopathies - ... TerrierBen #Inflammatory ... #Myopathies #Idiopathic ... #Myopathy #Comparison
Idiopathic Inflammatory Myopathies (IIM's)

RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's)

 • Overlap Myositis
Idiopathic Inflammatory ... Myopathies (IIM's ... myopathies (IIM's ... myopathy that occurs ... myopathy affecting
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy
 • Central or peripheral neurologic disease
That May Mimic Inflammatory ... Myopathy • Central ... • Metabolic myopathies ... Mitochondrial myopathy ... MuscleWeakness #Myopathy
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Myoglobinuria DDX: • Inflammatory ... , toxic myopathy ... Statins → Inflammatory ... myopathies such ... : Inflammatory statin
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
Critical Illness Myopathy ... - Metabolic Myopathies ... toxoplasmosis - Inflammatory ... myopathy: dermatomyositis ... polymyositis, necrotizing myopathy
Seronegative Inflammatory Arthritis - Differential Diagnosis
 • Seronegative Rheumatoid Arthritis 
 • Infectious Arthritis: Viral, Bacterial,
Seronegative Inflammatory ... Still's Disease, Inflammatory ... Myopathy • Crystal ... #Seronegative #Inflammatory
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
spinal cord • Inflammatory ... Paraneoplastic syndrome • Inflammatory ... proximal weakness Myopathy ... : • Inflammatory ... • Metabolic myopathies
Abdominal Distention - Differential Diagnostic Algorithm
Ascites
Bowel Dilatation
Other Causes
Mechanical Obstruction
 • Adhesions 60%
 • Volvulus 3%
 •
Megacolon • Inflammatory ... • Ischemic Myopathic ... Scleroderma • Familial Myopathy
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
Inflammatory Myopathies ... BrighamChiefs #Inflammatory ... #Myopathies #differential