24 results
IBS-C Pharmacotherapy

Polyethylene glycol
Lubiprostone
Linaclotide
Plecanatide
Tegaserod
Tenapanor

#IBSC #IBS #Constipation #Irritable #Bowel #Syndrome #pharmacology #table #comparison #management #treatment
Irritable #Bowel #Syndrome ... #pharmacology # ... table #comparison ... #management #treatment
IBS-D Pharmacotherapy

Loperamide
Rifaximin
Eluxadoline
Alosetron
Antispasmodics
Tricyclic antidepressants
SSRIs

#IBSD #IBS #Diarrhea #Irritable #Bowel #Syndrome #pharmacology #table #comparison #management #treatment
Irritable #Bowel #Syndrome ... #pharmacology # ... table #comparison ... #management #treatment
Vasopressors Demystified

Shock comes in many flavors and so do vasopressors. Here’s a OnePager summarizing my approach
Vasopressors #Basics #CriticalCare ... #Management #Pharmacology ... #Comparison #Inotropes
Pressors and Inotropes

Norepinephrine
 • alpha1 > beta 1
 • Increase SVR > Inotropy
Vasopressin
 • V1
 •
Pressors #Inotropes #criticalcare ... #pharmacology # ... comparison #shock ... #management
Acute Respiratory Distress Syndrome – ARDS: Clinical Cheat Sheet

An acute diffuse, inflammatory lung injury, leading to
Respiratory Distress Syndrome ... there is no clear cause ... the underlying cause ... RespiratoryDistress #Syndrome ... #CriticalCare
Neurological Side Effects of Antipsychotic Drugs
Acute dystonia - Spasm of muscles of tongue, face, neck, back
Antipsychotic Drugs Acute dystonia ... Neuroleptic malignant syndrome ... tremor ("rabbit syndrome ... #SideEffects #pharmacology ... #management
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
rapidly fatal • Causes ... Neuroleptic malignant syndrome ... ; Serotonin syndrome ... #Hyperthermia #comparison ... #diagnosis #management
Shock - Differential Diagnosis Framework
MAP = CO x SVR
Hypovolemic (↓ Intravascular volume):
 • Hemorrhage, dehydration due
findings based on cause ... anaphylaxis, release syndrome ... Diagnosis #table #comparison ... #criticalcare
Vasopressors and Inotropes
 • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
Vasopressors #Inotropes #management ... #criticalcare # ... summary #comparison ... #table #pharmacology
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
Bradyarrhythmias, Some cases ... Vasopressors #Inotropes #comparison ... #table #pharmacology ... #criticalcare