17 results
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... water Extrarenal hypotonic ... salt intake: • Hypertonic ... Differential #Diagnosis #Causes ... #nephrology #sodium
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Physiologic Approach to Hypotonic ... time you have a case ... of hypotonic hyponatremia ... #Physiologic #Hypotonic ... differential #diagnosis #table
Hyponatremia - Differential Algorithm
Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP
Hypotonic Hyponatremia: 
 • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
Differential Algorithm Isotonic ... , Recent TURP Hypotonic ... Hypothyroidism Hypertonic ... Algorithm #diagnosis #causes ... #nephrology #sodium
REBEL Review 71: Treatment of Thyroid Storm 

Propranolol 
Esmolol 
Propylthiouracil (PTU) 
Methimazole 
Saturated Solution of Potassium
Lugol's Solution Sodium ... Hydrocortisone #endocrinology ... hyperthyroidism #table ... management #treatment #pharmacology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... hypokalemia); nausea ... aspiration #Potassium #Binding ... #medications #pharmacology ... #table #comparison
Management of Hyponatremia
Hypertonic Saline - Only indicated if patient has severe symptoms + Na < 125
Give
• Discuss with endocrinology ... — discuss with endocrinology ... SIADH — look for cause ... hourly • Identify Cause ... algorithm #treatment #sodium
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
Hyponatremia is usually caused ... vast majority of cases ... 1) Is it hypotonic ... the underlying cause ... management #nephrology #sodium
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
while retaining sodium ... , which causes increased ... this pathway, ending ... because of the sodium ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... works by directly binding ... this pump, those sodium ... intracellular calcium causes ... CaitEKulig #Digoxin #Pharmacology
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... Januvia) - Once/day tablet ... not definitively cause ... DPP4 #Inhibitors #Pharmacology ... DM2 #diabetes #endocrinology