11 results
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... and Medication ... medications and ... #Pathophysiology ... #Drug #Endocrinology
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
Action for Common Diabetes ... Medications ... #Medications #pharmacology ... #pathophysiology ... #endocrinology
Potassium Channel Blockers - Medications
1. Cardiovascular Drugs
2. Psychiatric drugs
3. Other drugs
4. Synthetic opioids: Levomethadyl 
5. Opium
Channel Blockers - Medications ... ChannelBlockers #Medications ... #Differential #Diagnosis ... #Pharmacology # ... Toxicology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
class of anti-diabetic ... medications, with ... SGLT2 #Inhibitors #Pharmacology ... #Medications #DM2 ... #Diabetes #Endocrinology
Common sodium channel blockers which cause QRS widening.

Anticonvulsants: 
 - Carbamazepine 
Antidysrhythmics:  
 - Group
Antimalarial drugs ... widening #ECG #EKG #Pharmacology ... #Medications #Toxicology ... #Diagnosis #Differential ... #Drugs #Classes
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 • Metabolic acidosis with pH
Euglycemic Diabetic ... Significant Adverse Drug ... level < 200 mg/dL Pathophysiology ... Ketoacidosis #EuDKA #diagnosis ... #management #endocrinology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... #differential #diagnosis ... #pathophysiology ... #pharmacology # ... potassium #medications
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
thing about this drug ... This drug class ... Renal #Dosing #Pharmacology ... #Management #Diabetes ... #DM2 #Endocrinology
List of drugs causing acute intermittent porphyria.  James Dazhe Cao @JamesCaoMD, Dallas Tox @DallasTXTox
#Diagnosis #Pharmacology
List of drugs causing ... @DallasTXTox #Diagnosis ... #Pharmacology # ... Toxicology #Drugs ... #Induced #Medications
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
Correction of diabetic ... renal disease Drugs ... Hypomagnesemia #Causes #diagnosis ... #differential #medications ... #drugs #pharmacology