12 results
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... Ill-appearing, vital sign ... Mucocutaneous or ocular ... #Dermatology #Rash ... Targetoid #Algorithm #Differential
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
Landscaper w/ painless nodular ... wax and wane; diagnosis ... painless, no systemic signs ... biopsy preferred Differential ... Sporotrichiosis #Infection #clinical
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Ocular- 50%: Ptosis ... life-threatening Differential ... Bedside: ice pack ... test - Cogan sign ... - Peek sign
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
mass and NO prior signs ... or clinical history ... Differential diagnosis ... Tendon Sheath - Nodular ... #msk #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... Behcet syndrome (Clinical ... Behcet disease) Differential ... #management #signs ... #symptoms #rheumatology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... neutrophils are slightly less ... #Bandemia #differential ... #WBC #CBC #hematology ... #pathophysiology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... systemic sx + signs ... very remarkable w/differential ... Nice to be confident ... GCA #Temporal #Signs
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
infection (IFI) in hematologic ... cut-offs defined in clinical ... BAL GM does not differentiate ... - Frozen ice-pops ... Galactomannan #diagnosis
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Transverse Myelitis - Clinical ... • Bilateral signs ... Herpes zoster, West Nile ... management #neurology #differential
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Diagnosis Framework ... purpura: Strong sign ... purpura (lower legs ... #Diagnosis #Rheumatology