9 results
Tinea Capitis in a Newborn- A 3-week-old male newborn was brought to the pediatrician with three
Tinea Capitis in ... Tinea capitis, a ... #clinical #photo ... #NEJM #tinea #capitis ... #ringworm #derm
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
IgA Vasculitis – ... various inflammatory cells ... histopathologic term ... #HSP #IgA #Vasculitis ... Pathophysiology #Diagnosis #Signs
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
recurrent fevers, vasculitis ... hematopoietic stem cells ... blood myeloid cells ... NEJM Review: https ... Autoinflammatory #Somatic #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... purpura: Strong sign ... Multinucleated giant cells ... pulmonary infiltrates/cavities ... Differential #Diagnosis #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
, small-vessel vasculitis ... panuveitis, retinal vasculitis ... disease, ulcerative colitis ... diagnosis #management #signs ... #symptoms #rheumatology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
No necrosis, No vasculitis ... increased IgG4+ cells ... supporting long-term ... workup #treatment #rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic inflammatory vasculitis ... systemic sx + signs ... differential diagnosis = vasculitis ... them, but urgent rheumatology ... GCA #Temporal #Signs
Pyoderma Gangrenosum in Ulcerative Colitis- ...left chest (Panel A) and leg (Panel B). The physical examination
in Ulcerative Colitis ... leukocytoclastic vasculitis ... #clinical #photo ... #NEJM #pyoderma ... #derm
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Skin: - CLL cells ... or basket cells ... Contamination, colitis ... workup #oncology #hematology