6 results
Summary of dosing recommendations in renal impairment of commonly used hypoglycaemic agents

#Diabetes #Diabetic #Medications #Pharmacology #Dosing
Summary of dosing ... recommendations in renal ... #Pharmacology # ... #Impairment #CKD ... #Table #GFR #Hypoglycemics
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
Diabetes Medications ... Summary Table ... modifications Metformin ... Improved outcomes in CKD ... comparison #management #endocrinology
Management of Diabetes Mellitus in Patients With CKD

1. Monitor for changes in BP, serum creatinine, &
Patients With CKD ... patients with T2D, CKD ... and CKD should ... evidence-based pharmacologic ... #Diabetes #CKD #
Metformin in Diabetic Kidney Disease
Immediate release:
 • Initial 500 mg or 850 mg once daily
 •
Metformin in Diabetic ... maximum dose eGFR ... recommended dose eGFR ... < 30: Stop metformin ... #CKD #pharmacology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... Summary Mechanisms ... #Pharmacology # ... Summary #DM2 #diabetes ... #endocrinology
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Sulfonylureas - Pharmacology ... Summary Mechanisms ... contraindicated in CKD ... #Summary #DM2 # ... diabetes #endocrinology