3 results
Metformin in Diabetic Kidney Disease
Immediate release:
 • Initial 500 mg or 850 mg once daily
 •
Metformin in Diabetic ... maximum dose eGFR ... #CKD #pharmacology ... algorithm #management #kdigo ... #initiation #titration
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... Summary Mechanisms ... mitigated by slow titration ... #Pharmacology # ... Summary #DM2 #diabetes
Management of Diabetes Mellitus in Patients With CKD

1. Monitor for changes in BP, serum creatinine, &
ml/min per 1.73 m2 ... ADA/KDIGO Consensus ... evidence-based pharmacologic ... #Diabetes #CKD # ... ADA #KDIGO #eGFR