10 results
Diabetes Combination Tablets - Estimated A1c Lowering 
Metformin + DPP4 
• Janumet (metformin + sitagliptin) 
•
Diabetes Combination ... + DPP4 • Janumet ... dapagliflozin) Dpp4 ... Tablets #Oral #DM2 ... #Pharmacology #
Metformin - First Line Treatment for Diabetes Type 2
• Start with initial dose of 500 mg
Metformin - First ... form and consider using ... #Indications #Titration ... #Pharmacology # ... Diabetes #DM2 #Prescribing
Algorithm for Metformin Prescribing and Dosing in CKD
Dose Initiation - Immediate release:
 • Initial 500 mg
Algorithm for Metformin ... Prescribing and Dosing ... #CKD #pharmacology ... #algorithm #diabetes ... #titration
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... mitigated by slow titration ... EricsMedicalLectures/ #Metformin ... #Pharmacology # ... Summary #DM2 #diabetes
Oral Hypoglycemics in Diabetes Management
1  INSULIN SENSITIZER
 • TZD 
     -
Sensitivity - Metformin ... (Adlyxin) • DPP ... by inhibiting DPP ... #Management #pharmacology ... #DM2 #DMII #Classification
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Normal and Renal Dosing ... Inhibitors #Renal #Dosing ... #Pharmacology # ... Management #Diabetes ... #DM2 #Endocrinology
Metformin: Biguanide
Metformin is the first-line medication for treatment of type 2 diabetes. It is very effective
treatment of type 2 diabetes ... Additionally, titrating ... 2000 mg/day) and using ... #Pharmacology # ... Mechanism #Diabetes
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
to treat Type 2 Diabetes ... very similar to DPP4s ... GLP1 #Agonists #Pharmacology ... #Dosing #Diabetes ... #DM2 #Endocrinology
GLP-1 Medications: Ozempic vs. Trulicib (semaglutide vs. dulaglutide) 

From my experience, Ozempic and Trulicity are the
not require dose titration ... Hopefully this overview ... options after metformin ... #dulaglutide #Pharmacology ... #Diabetes #Comparison
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist
Dosing:
3 mg daily x 30 days, then 7 mg
GLP-1 Agonist Dosing ... has a similar titration ... empagliflozin and DPP4 ... #semaglutide #Diabetes ... #Pharmacology #