14 results
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
Medications ... Meglitinides • GLP ... Receptor Agonists • DPP4i ... #Medications #pharmacology ... pathophysiology #endocrinology
Diabetes Combination Tablets - Estimated A1c Lowering 
Metformin + DPP4 
• Janumet (metformin + sitagliptin) 
•
Diabetes Combination ... + DPP4 • Janumet ... Tablets #Oral #DM2 ... #Pharmacology # ... Pills #Endocrinology
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
Diabetes Medications ... modifications Metformin ... Sulfonylureas GLP ... events TZDs DPP ... #dm2
Diabetes Medication Choice
-Diabetes Medication Choice decision aid cards provide information on medications commonly used to treat
Diabetes Medication ... - To date only metformin ... , SGLT-i, GLP1 medications ... #Type2 #DM2 #PatientInfo ... Reduction #Costs #Pharmacology
Effects on body weight of various classes of type-2 diabetes medications.
 - Metformin - Weight Loss
medications ... - Metformin - ... Weight Loss ++ - GLP ... Weight Loss +++ - DPP ... weightgain #comparison #pharmacology
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
to treat Type 2 Diabetes ... very similar to DPP4s ... #Pharmacology #Dosing ... #Diabetes #DM2 ... #Endocrinology
Metformin - First Line Treatment for Diabetes Type 2
• Start with initial dose of 500 mg
Metformin - First ... Treatment for Diabetes ... form and consider using ... #Pharmacology # ... Diabetes #DM2 #Prescribing
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology ... normally inactivates GLP ... #Inhibitors #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Normal and Renal Dosing ... Increase Incretins (GLP-I ... #Pharmacology # ... Management #Diabetes ... #DM2 #Endocrinology
Oral Hypoglycemics in Diabetes Management
1  INSULIN SENSITIZER
 • TZD 
     -
Sensitivity - Metformin ... (Adlyxin) • DPP ... by inhibiting DPP ... #Management #pharmacology ... #DM2 #DMII #Classification