7 results
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
on MRI studies ... Causes of false- ... negative SPEP: ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
cord compression (MRI ... compressive cord lesion ... less swollen - Lesion ... tested and if negative ... or optic nerve lesions
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Pustular skin lesions ... Rule out other causes ... - MRI: inflammation ... #Rheumatology # ... diagnosis #management #Dermatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
levels >1g/L • Negative ... causes of secondary ... Antiphospholipid syndrome ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
ischemic skin lesions ... Conjunctivitis, mucositis ... oligoclonal bands • MRI ... tract, and often causes ... Differential #Diagnosis #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK ... Symptomatic: artificial tears ... #Rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
ischemic skin lesions ... tract, and often causes ... Conjunctivitis, mucositis ... well as inner ear ... differential #diagnosis #rheumatology