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diagnosis rheumatology management neurology vasculitis bee classification clinical cryofibrinogenemia deposition gammopathies hadd hydroxyapatite mgus monoclonal multiplemyeloma myelitis noninflammatory oncology radiology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
focal lesions on MRI ... Causes of false- ... negative SPEP: ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
super-antigen mediated disease ... tested and if negative ... Pallidum - Lyme Disease ... MCTD - Bechet disease ... management #neurology #differential
Hydroxyapatite Deposition Disease (HADD) - MSK Radiology Imaging Findings: • Ovoid hypointense structures along the bursal surface
(HADD) - MSK Radiology ... consistent with myositis ... Case description ... specificity of tear ... #clinical #mri
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Non-inflammatory Causes ... Brain, Eye, and Ear ... neuropathy (LHON) plus MRI ... consistent with MS ... noninflammatory #differential
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
levels >1g/L • Negative ... cryoglobulins • Negative ... causes of secondary ... Antiphospholipid syndrome ... #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... affected areas and if negative ... - MRI: inflammation ... osteoarticular and skin disease ... diagnosis #management #Dermatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... neuropathy, transverse myelitis ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK ... Symptomatic: artificial tears
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... tract, and often causes ... Conjunctivitis, mucositis ... well as inner ear ... disease Differential
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Conjunctivitis, mucositis ... oligoclonal bands • MRI ... tract, and often causes ... Diagnosis #Rheumatology
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