37 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... test, ANA (e.g., SLE ... changes), high MCV anemia ... #Causes #Workup
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... - Hemolytic anemia ... Splenomegaly - CTD (SLE ... Associated - SLE ... #Differential #Diagnosis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... • Immunologic Workup ... Positive in 60-80% of cases ... pANCA anti-MPO - Negative ... #rheumatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... evaluation or workup ... organ-specific signs ... #Differential #diagnosis ... #hematology #eosinophilia
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... pANCA anti-MPO - Negative ... #comparison #table ... #rheumatology # ... diagnosis #management
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
neurocognitive disorders ... Alzheimer - 1st cause ... - Progressive amnesia ... (parkinsonian signs ... Dementia - 2nd cause
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... Neoplastic / Hematologic ... • Anemia • ... Arthritis • SLE ... • Somatization Disorder
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... Abnormality • SLE ... Iron deficiency anemia ... #Differential #Diagnosis ... #Algorithm #causes
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... genotypes): SS, SC, SE ... Consider RBC membrane disorder ... #Algorithm #workup ... #hematology #testing
Generalized Seizures and Pseudoseizures
Generalized seizures "are conceptualized as originating as some point within, and rapidly engaging,
and metabolic causes ... drugs, uremia, ... Classification #Diagnosis ... #Neurology #Signs ... #Symptoms #Comparison