9 results
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Headaches • Pale skin ... Difficulty breathing • Neutropenia ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... Cytopenias: • Neutropenia ... , anemia, thrombocytopenia ... Leukemia #diagnosis #workup ... #oncology #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... antiglobulin tests - Negative ... WBC count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... Myeloproliferative Disease • Neutropenia ... blood count with differential ... Syndromes #diagnosis #hematology ... #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
- infiltrates (anemia ... or functional neutropenia ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... gammopathy, and skin ... gastric tumors • Hematology ... Gap #ProteinGap #differential ... #diagnosis #hematology
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
marrow biopsy negative ... • No CRAB - no anemia ... #Plasmacytoma #Oncology ... #Diagnosis #Workup ... #Hematology