9 results
Fungal biomarkers
Beta-d-glucan
Aspergillus galactomannan

By Dr. Sara Dong @swinndong via Febrile [febrilepodcast.com]

#ID  #Infectious Diseases  #Infections
#Differential #Ddx
Fungal biomarkers ... #Infections #Differential ... #Ddx #Diagnosis ... #Fungal #Fungi ... Aspergillus #Candida #Microbiology
Important Fungal Stains
Mycology Lab:
 • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
Important Fungal ... and chitin in fungal ... • India ink - "Negative ... #microbiology #microscopy ... #fungus #comparison
Blood culture contaminants
Grouped by gram negative vs gram positive vs other as well as never/maybe/probably
Some additional
Grouped by gram negative ... #Infections #Microbiology ... #Micro #Differential ... #Ddx #Diagnosis
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
blood culture negative ... Tropheryma whipplei, Fungi ... BCNIE #Causes #differential ... causes #culture #negative ... InfectiousDiseases #Microbiology
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
Fungal Biomarkers ... Coccidioides - Negative ... Cryptococcus - Negative ... BAL GM does not differentiate ... Galactomannan #diagnosis #comparison
Liver infections and imaging findings
 - Pyogenic Liver Abscess
 - Amebic Abscess
 - Cholangitic Microabscesses
- Disseminated Fungal ... Infection DDx of ... imaging #radiology #Differential ... #Ddx #Diagnosis ... #Microbiology
Timeline of infections after solid organ transplantation can roughly be broken up into three time periods:
#Infections #Differential ... #Ddx #Diagnosis ... Transplant #TxID #SOT #Comparison ... #Microbiology
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
component of many fungi ... Almost always negative ... Spec 81% for dx ... in BAL does not differentiate ... closely related fungi
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
- Overview and Differential ... Hypercoagulable (APLAS) Microbiology ... aureus, Coagulase-negative ... Glomerulonephritis DDX ... #Endocarditis #Differential