12 results
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
Autoimmune Hemolytic ... Anemia (AIHA) Pathophysiology ... C3 positive or negative ... #Anemia #Pathophysiology ... #diagnosis #hematology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Anemia (AIHA) - Differential ... AIHA (7-8%) DAT-negative ... #Autoimmune #Hemolytic ... Diagnosis #Table #hematology
Hepatic Masses on MRI - Differential Diagnosis by MRI Findings

Masses: Hemangioma, Adenoma, FNH, HCC, Fibrolamellar HCC,
- Differential ... Diagnosis by MRI ... #differential # ... diagnosis #liver #hepatology ... #radiology #mass
Appearance of Liver Lesions on Various Imaging Modalities
 • Computed Tomography (CT) - Arterial Phase, Portal
Resonance Imaging (MRI ... #Contrast #CT #MRI ... #POCUS #radiology ... #differential # ... table #appearance #hepatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
hemorrhage and hemolysis ... intravascular hemolysis ... antiglobulin tests - Negative ... WBC count and differential ... Diagnosis #Workup #Hematology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
focal lesions on MRI ... Causes of false- negative ... MGUS #diagnosis #hematology ... #oncology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Diagnosis: • hemolytic ... for anti-C3d and negative ... • Compensated hemolysis ... younger pts) Differential ... #anemia #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... initiation • Differential ... diagnosis #management #hematology ... #oncology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Neutrophil (Normal) Differential ... likelihood of negative ... #Bandemia #differential ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Coombs (-) hemolytic ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology