6 results
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
Secondary Syphilis ... soles in 50% of cases ... and nephrotic syndrome ... have positive serology ... granuIomas on skin
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
responsible for most cases ... treatment. 2) Secondary ... weight loss • Skin ... Albuminuria, nephrotic syndrome ... ulcerated • MSK
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
• Loose anagen syndrome ... decalvans - Secondary ... to Skin Disease ... syphilis #Diffuse ... Diagnosis #Algorithm #causes
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
levels >1g/L • Negative ... cryoglobulins • Negative ... causes of secondary ... Antiphospholipid syndrome ... #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
weeks) Can Be Caused ... aureus • Gram-negative ... tuberculosis) • Fungi, secondary ... syphilis Chronic ... Differential #Diagnosis #MSK
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... other diseases • Secondary ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK