16 results
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
hydrocephalus, HIV ... ... laboratory tests ... Aphaso-apraxo-agnosia syndrome ... (parkinsonian signs ... Frontal atrophy Vascular
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
and diplopia) • Vascular ... Positive pathergy test ... is a skin prick test ... #signs #symptoms ... #rheumatology #
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
- Differential Diagnosis ... Seronegative Reactive Syndrome ... Effusions: - Hematologic ... #differential #diagnosis ... #msk #physicalexam
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Hyperviscosity, - Vascular ... levels >1g/L • Negative ... • TTP, HUS and HIT ... Antiphospholipid syndrome ... hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Disruptions in vascular ... ITP - APLS - HIT ... Fecal occult blood test ... #physicalexam
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... for anti-C3d and negative ... Mycoplasma, EBV, HIV ... test #cold # ... hemolytic #anemia #hematology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
e.g., congenital hip ... osteopetrosis, avascular ... #Joint #Pain #MSK ... #rheumatology # ... #differential #diagnosis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Arthritis Differential Diagnosis ... spine, shoulders, hips ... noninflammatory Signs ... aureus • Gram-negative ... #MSK #rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
adults in the west ... Agent Orange or Hep ... Physical Exam/Signs ... • Richter’s Syndrome ... workup #oncology #hematology
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
- Differential Diagnosis ... , Loose anagen syndrome ... Examination: • Signs ... disease • Pull test ... Initial Laboratory Tests