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differential rheumatology arthritis causes pain vasculitis agglutinin algorithm anemia approach classification cold cryofibrinogenemia dermatology disease effusions gout hemolytic knee management
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Arthritis Differential Diagnosis ... spine, shoulders, hips ... noninflammatory Signs ... aureus • Gram-negative ... #MSK #rheumatology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
present both at rest ... e.g., congenital hip ... osteopetrosis, avascular ... #Pain #MSK #rheumatology ... #differential #diagnosis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... for anti-C3d and negative ... Mycoplasma, EBV, HIV ... test #cold # ... hemolytic #anemia #hematology
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
- Differential Diagnosis ... Fever/Chills/Joint ... Effusions: - Hematologic ... #differential #diagnosis ... #msk #physicalexam
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Disruptions in vascular ... Palpable Rash: - Autoimmune ... Fecal occult blood test ... #physicalexam
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Hyperviscosity, - Vascular ... associated with autoimmune ... • TTP, HUS and HIT ... Antiphospholipid syndrome ... hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... pulse deficits vascular ... of shoulder and hip ... eruption • Joints ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
eruption - Joints ... purpura: strong sign ... retinopathy Lab Tests ... Cryoglobulins • HIV ... #rheumatology #
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
deposition in joints ... sex • Metabolic syndrome ... attacks • Other joints ... Needle-shaped, negatively ... double contour sign
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Tests: • Measure ... papules and Gottron sign ... ) • Shawl sign ... : Fever, joint pain ... weakness + atrophy- Hip
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