12 results
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Arthritis Differential Diagnosis ... spine, shoulders, hips ... noninflammatory Signs ... aureus • Gram-negative ... #MSK #rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... for anti-C3d and negative ... chills, flank pain ... test #cold # ... hemolytic #anemia #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Disruptions in vascular ... lesions • Severe pain ... Palpable Rash: - Autoimmune ... Fecal occult blood test ... #physicalexam
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
present both at rest ... e.g., congenital hip ... osteopetrosis, avascular ... #MSK #rheumatology ... #differential #diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
and diplopia) • Vascular ... is a skin prick test ... Nonsurgical abdominal pain ... #signs #symptoms ... #rheumatology #
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
- Differential Diagnosis ... Fever/Chills/Joint pain ... Effusions: - Hematologic ... #differential #diagnosis ... #msk #physicalexam
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Hyperviscosity, - Vascular ... associated with autoimmune ... • TTP, HUS and HIT ... Antiphospholipid syndrome ... hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
and bullous or vesicular ... purpura: strong sign ... retinopathy Lab Tests ... Cryoglobulins • HIV ... #rheumatology #
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
or without back pain ... bouts of HTN Diagnostic ... • Bilateral signs ... tested and if negative ... , MOG-IgG test should
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... purpura: Strong sign ... pulse deficits vascular ... of shoulder and hip ... #Rheumatology