25 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Kasabach-Merritt syndrome ... Ig A vasculitis/HSP ... #hematology #rheumatology ... #nonpalpable #dermatology
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
Stevens-Johnson Syndrome ... Staphylococcal scalded skin syndrome ... differentiating between the diagnosis ... #TEN #Dermatology ... #PhysicalExam #
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Disruptions in vascular ... Fecal occult blood test ... Algorithm #Causes #dermatology ... #physicalexam
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
hydrocephalus, HIV ... ... laboratory tests ... Aphaso-apraxo-agnosia syndrome ... (parkinsonian signs ... Frontal atrophy Vascular
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
and diplopia) • Vascular ... Positive pathergy test ... is a skin prick test ... #signs #symptoms ... #rheumatology #
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... for anti-C3d and negative ... Mycoplasma, EBV, HIV ... test #cold # ... hemolytic #anemia #hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Hyperviscosity, - Vascular ... levels >1g/L • Negative ... • TTP, HUS and HIT ... Antiphospholipid syndrome ... hematology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
- Differential Diagnosis ... Seronegative Reactive Syndrome ... Effusions: - Hematologic ... #differential #diagnosis ... #msk #physicalexam
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
• A clinical diagnosis ... affected areas and if negative ... blockers had the best ... diagnosis #management ... #Dermatology
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
- Differential Diagnosis ... , Loose anagen syndrome ... Examination: • Signs ... disease • Pull test ... #dermatology #Hairloss