16 results
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Disruptions in vascular ... lesions • Severe pain ... Fecal occult blood test ... Algorithm #Causes #dermatology ... #physicalexam
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... affected areas and if negative ... blockers had the best ... diagnosis #management ... #Dermatology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
present both at rest ... e.g., congenital hip ... osteopetrosis, avascular ... #MSK #rheumatology ... #differential #diagnosis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Arthritis Differential Diagnosis ... spine, shoulders, hips ... noninflammatory Signs ... aureus • Gram-negative ... #MSK #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
and diplopia) • Vascular ... is a skin prick test ... Nonsurgical abdominal pain ... #signs #symptoms ... #rheumatology #
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... for anti-C3d and negative ... chills, flank pain ... test #cold # ... hemolytic #anemia #hematology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
- Differential Diagnosis ... Fever/Chills/Joint pain ... Effusions: - Hematologic ... #differential #diagnosis ... #msk #physicalexam
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Hyperviscosity, - Vascular ... levels >1g/L • Negative ... • TTP, HUS and HIT ... Antiphospholipid syndrome ... hematology
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
- Differential Diagnosis ... , Loose anagen syndrome ... Examination: • Signs ... disease • Pull test ... #dermatology #Hairloss
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
adults in the west ... Agent Orange or Hep ... Physical Exam/Signs ... • Richter’s Syndrome ... workup #oncology #hematology