14 results
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
hydrocephalus, HIV ... ... laboratory tests ... Aphaso-apraxo-agnosia syndrome ... (parkinsonian signs ... Frontal atrophy Vascular
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
, small-vessel vasculitis ... and diplopia) • Vascular ... is a skin prick test ... #signs #symptoms ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
and bullous or vesicular ... purpura: strong sign ... retinopathy Lab Tests ... Cryoglobulins • HIV ... #rheumatology #
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Disruptions in vascular ... deficiency Work ... Fecal occult blood test ... #physicalexam
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
- Differential Diagnosis ... Lack of UMN/LMN signs ... parainfluenza, Coxsackie, HIV ... dystrophies Work ... #Differential #Diagnosis
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup ... and Differential Diagnosis ... patients with a negative ... Causes: • Vascular ... Coarctation of aorta, Vasculitis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... purpura: Strong sign ... pulse deficits vascular ... of shoulder and hip ... #Rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Hyperviscosity, - Vascular ... malignancies, vasculitis ... • TTP, HUS and HIT ... Antiphospholipid syndrome ... hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Cold Agglutinin Syndrome ... for anti-C3d and negative ... test #cold # ... hemolytic #anemia #hematology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
e.g., congenital hip ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup ... #differential #diagnosis