11 results
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... activates lipolysis Signs ... /Symptoms: • GH ... #FeedbackLoop #endocrinology ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... GH excess prior ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
shoe size, ↑ heel-pad ... malignancy Pathophysiology ... • GH stimulates ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
Symptoms: Commonly no signs ... Bone/joint pain Psychiatric ... Hyperparathyroidism #diagnosis #endocrinology ... Secondary #Tertiary #pathophysiology
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
the etiology Signs ... myxedema - Fat pad ... GravesDisease #pathophysiology ... #endocin #endocrinology ... #symptoms #signs
Schizophrenia: Pathogenesis and Symptoms
Increased dopaminergic transmission in mesolimbic projection
-> Dopaminergic neurons here project into the limbic
thought to cause Negative ... Schizophrenia #pathophysiology ... diagnosis #symptoms #signs ... #psychiatry #positive ... #negative
Social Anxiety Disorder (SAD) - Pathophysiology 
Excessive fear of one or more social situations
 • Safety
Anxiety Disorder (SAD ... ) - Pathophysiology ... #Pathophysiology ... diagnosis #symptoms #signs ... #psychiatry
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
following order; GH ... Signs / Symptoms ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Gangrenous cholecystitis with sloughed, intraluminal membranes on POCUS
Worsening RUQ pain/fever. Ill-appearing, low BP. WBC 22.4K. POCUS
intraluminal membranes on POCUS ... POCUS GB done. ... US Murphy's sign ... is negative generally ... cholecystitis #POCUS
Seasonal Affective Disorder: Pathogenesis and clinical findings

Symptoms (included in the DSM-V) - Two Major Depressive episodes
non-seasonal episodes #SAD ... MoodDisorders #Diagnosis #Pathophysiology ... #Signs #Symptoms ... #Psychiatry