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diagnosis hematology hemolytic hodgkins lymphoma oncology agglutinin aiha bandemia cbc cold disease drugs erythematosus hypnotic inflammatory lupus management medications myopathies
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Anemia (AIHA) - ... Table Warm AIHA ... AIHA (7-8%) DAT-negative ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... EBV infection, Autoimmune ... Pylori) - Autoimmune ... translocation • Types: Classification ... #hematology
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
exclusion Necrotizing Autoimmune ... Inflammatory #Myopathies #differential ... #diagnosis #comparison ... #rheumatology # ... table
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Neutrophil (Normal) Differential ... Corticosteroid use • Autoimmune ... likelihood of negative ... #differential # ... neutrophil #WBC #CBC #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... for anti-C3d and negative ... CLL (older) • Autoimmune ... younger pts) Differential ... #hematology #diagnosis
Sedative-Hypnotic Drugs Benzodiazepines: - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
Sedative-Hypnotic ... relief of anxiety • amnesia ... relief of anxiety • amnesia ... #medications #pharmacology ... #comparison #table
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunosuppression • Autoimmune ... Weight loss • Anemia ... Immune hemolytic anemia ... -95% of cases) Classification ... Immunohistochemical studies (to differentiate
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... permanent alopecia Differential ... disease • Non-autoimmune ... rheumatologic diseases ... lymphopenia, low PLT • Anemia
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