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diagnosis obstetrics pregnancy biliary cholangitis comparison disease injury lfts liverenzymes obgyn pbc primary workup
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... (DIC, ascites, jaundice ... Preeclampsia, HELLP ... #Fatty #Liver # ... Pregnancy #hepatology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Pruritus, Mild jaundice ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... #comparison #differential ... #HELLP #AFLP
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Pregnancy - AFLP ... , HELLP Moderate ... • Alcoholic hepatitis ... #Causes
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Vascular Causes ... • Pregnancy: HELLP ... : < 1 • Cirrhosis ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... hyperpigmentation • Jaundice ... bile ducts Differential ... Diagnosis: • Viral hepatitis
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