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liver pregnancy biliary cholangitis comparison disease fatty hellp hepatitis icp interpretation lfts obgyn pathophysiology pbc primary rvalue transaminitis workup
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
(DIC, ascites, jaundice ... infiltration) Differential ... Liver #Pregnancy #hepatology ... #obstetrics #obgyn ... #diagnosis #management
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Pruritus, Mild jaundice ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... #comparison #differential ... #diagnosis #icp
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
(Alk phos/ULN ALP ... hepatitis: < 1 • Cirrhosis ... Hemolysis #liver #chemistry ... #diagnosis #differential ... #Hepatology #transaminitis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary Cirrhosis ... hyperpigmentation • Jaundice ... obstruction • ALP ... bile ducts Differential ... #workup #hepatology
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