8 results
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Hypernatremia Diagnosis ... Workup Step 1 ... mmol/L - true hyponatremia ... EUVOLEMIC • SIADH ... renal failure #Hypernatremia
Cancer agents and Electrolyte Disorders
 • Hypocalcemia: Cisplatin from Low Mg, Cetuximab- due to low Mg
Axitinib,
Cancer agents and ... Electrolyte Disorders ... Trastuzumab • Hyponatremia ... resistance, PD-1 ... Methotrexate- SIADH
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... water retention 1) ... Low Uric Acid → SIADH ... Rachel Stern MD #Hyponatremia ... #nephrology #sodium
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Hypernatremia - ... 1) Check Urine ... Extrarenal Hypernatremia ... Ingestion Renal Hypernatremia ... MatthewHoMD #Hypernatremia
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Approach to Hypotonic Hyponatremia ... case of hypotonic hyponatremia ... normal volume-based algorithm ... +K / serum Na >1 ... Physiologic #Hypotonic #Hyponatremia
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
Options 1. ... food has water • Electrolyte ... purposes, restrict to 1 ... #Management #hyponatremia ... #nephrology #treatment
Hyponatremia Differential Diagnosis Algorithm in Cancer
UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Hyponatremia Differential ... inappropriate • SIAD ... adrenalitis; PD-1 ... metastases) #Hyponatremia ... #algorithm #nephrology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
of breath • Neurologic ... • Early death Neutropenic ... possible coma SIADH ... : • Hyponatremia ... differential #diagnosis #cancer