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diagnosis differential causes lactic nephrology classification criticalcare elevation gitelman heat heatstroke illness pathophysiology rhabdomyolysis stroke treatment typea typeb
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
Hypotension & Hypovolemia ... Ischemia, Compartment Syndrome ... Hypothermia & Shivering, Seizures ... toxic alcohols, Sodium ... in Short Bowel Syndrome
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... alkalosis • Normal or low ... Renal tubular acidosis ... tachycardia • Seizures ... diagnosis #nephrology #management
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
circulation If drugs, seizures ... Heavy exercise - Seizures ... - Shock - Hypovolemia ... LV failure - Low ... - Compartment syndrome
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Dehydration - Loss of sodium ... conditions - Neurogenic ... heat illness → Hypernatremia ... consciousness, Coma/seizure ... - Hyperkalemia
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Framework and Management ... exertion/training - Seizures ... Hyperuricemia • Hyponatremia ... Isotonic fluid/Lactated ... Differential #Diagnosis #Management
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