11 results
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
• Euvolemic (Low ... insipidus (central or nephrogenic ... Hypervolemic: Conn syndrome ... , Cushing syndrome ... Algorithm #nephrology #sodium
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Compartment syndrome ... exertion/training - Seizures ... Dermatomyositis Clinical ... Hyperuricemia • Hyponatremia ... or compartment syndrome
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Dehydration - Loss of sodium ... conditions - Neurogenic ... sweat Heat Injury ... heat illness → Hypernatremia ... consciousness, Coma/seizure
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
causing endothelial injury ... Hyperviscosity Syndrome ... : • Clinical triad ... factor level • Low ... diagnosis #types #classification
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
liver or renal injury ... Heavy exercise - Seizures ... LV failure - Low ... - Compartment syndrome ... #typea #typeb #classification
Hypertensive Disorders of Pregnancy
Chronic Hypertension:
 • Guidelines as SBP ≥130 or DBP ≥ 90 mmHg
 •
evidence of organ injury ... : Tonic-clonic seizure ... patients • HELLP: Syndrome ... liver enzymes, Low ... diagnosis so have high clinical
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... anti-Smith Ab, low ... Skin Disease Classification ... Clinical Features ... , lymphopenia, low
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... tubule (DCT) Clinical ... alkalosis • Normal or low ... tachycardia • Seizures
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
neuromuscular injury ... the epithelial sodium ... Drug-associated: heparin, low-molecular-weight ... antiphospholipid syndrome ... High #Potassium #Classification
Toaster Electrocution Electrical Injury
Primary determination of injury extent = amount of CURRENT flowing through body.
VARIABLES: voltage,
Low-Voltage <1000V ... coagulation, compartment syndrome ... CNS- stroke, seizure ... arrest (arrthymia), seizure ... #clinical #video