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differential causes classification algorithm hematology management vasculitis acidosis activation aplastic cryoglobulinemia cryoglobulins elevation erythematosus heat heatstroke high hyperkalemia illness lactate
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis ... • Euvolemic (Low ... , Cushing syndrome ... #Differential #Diagnosis ... Algorithm #nephrology #sodium
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
Causes of Seizures ... - Differential Diagnosis ... vasoconstriction syndrome ... Traumatic brain injury ... Hyperglycemia, Hyponatremia
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low ... Differential Diagnosis ... , lymphopenia, low ... PLT • Anemia of ... #Rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Marrow (Toxic injury ... Constitutional Syndromes ... may result from low ... #oncology #hematology ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
SJIA], systemic lupus ... with leukopenia, anemia ... 10,000 ng/mL • Hyponatremia ... #Diagnosis #Management ... #Hematology #Rheumatology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
- Differential Diagnosis ... Dehydration - Loss of sodium ... conditions - Neurogenic ... heat illness → Hypernatremia ... consciousness, Coma/seizure
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
causing endothelial injury ... Labs/Diagnosis: ... factor level • Low ... (e.g. systemic lupus ... classification #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... inflammation Others: • Lupus ... such as systemic lupus ... • Complement (Low ... #rheumatology #
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
neuromuscular injury ... diseases: syßtemic lupus ... Drug-associated: heparin, low-molecular-weight ... antiphospholipid syndrome ... #Differential #Diagnosis
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
liver or renal injury ... Heavy exercise - Seizures ... LV failure - Low ... - Compartment syndrome ... 30mmHg) - Severe anemia
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