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diagnosis differential algorithm causes hyponatremia management gitelman heat heatstroke hypotonic illness neurology pathophysiology physiologic rhabdomyolysis stroke table treatment workup
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
• Euvolemic (Low ... Hypervolemic: Conn syndrome ... , Cushing syndrome ... Workup #Algorithm #nephrology ... #sodium
Modified Hyponatremia Algorithm Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants Hypotonic Hyponatremia: • ADH ON (UOsm > 100):
ON (UNa < 30): Hypovolemia ... Cirrhosis, Nephrotic syndrome ... Primary polydipsia, Low ... Algorithm #diagnosis #sodium ... #nephrology
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
Causes of Seizures ... vasoconstriction syndrome ... Traumatic brain injury ... Hyperglycemia, Hyponatremia ... Hypomagnesemia, Hypocalcemia
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Compartment syndrome ... - Electrical ... exertion/training - Seizures ... Hyperuricemia • Hyponatremia ... causes #treatment #nephrology
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
: SIADH, Renal Sodium ... can be high or low ... Present (Uosm ≥100): Hypovolemia ... Cirrhosis, Nephrotic syndrome ... #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... alkalosis • Normal or low ... tachycardia • Seizures ... #diagnosis #nephrology
Hyponatremia - Differential Algorithm Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP Hypotonic Hyponatremia: • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
Hyponatremia - Differential ... : • Hypovolemia ... Cirrhosis, Nephrotic Syndrome ... diagnosis #causes #nephrology ... #sodium #low
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Dehydration - Loss of sodium ... conditions - Neurogenic ... sweat Heat Injury ... heat illness → Hypernatremia ... consciousness, Coma/seizure
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