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diagnosis differential algorithm hyponatremia management lactic treatment alkalosis chloride classification criticalcare elevation gitelman heat heatstroke hypokalemia hypotonic illness metabolic pathophysiology
Hypernatremia - Differential Diagnosis Workup Algorithm 1) Check Urine Osmolality: > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis Workup ... • Euvolemic (Low ... , Cushing syndrome ... #Algorithm #nephrology ... #sodium
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
Ischemia, Compartment Syndrome ... Hypothermia & Shivering, Seizures ... Beta-Agonists, ↑ work ... toxic alcohols, Sodium ... in Short Bowel Syndrome
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Causes of Lactate ... Causes of Lactate ... Heavy exercise - Seizures ... LV failure - Low ... - Compartment syndrome
Hyponatremia - Diagnosis and Treatment Hyponatremia is usually caused by the inability to excrete water normally.
3 questions to work ... demyelination syndrome ... of symptomatic (seizures ... Treatment #management #nephrology ... #sodium
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... : SIADH, Renal Sodium ... can be high or low ... Cirrhosis, Nephrotic syndrome ... #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
alkalosis • Normal/low ... , Gitelman syndrome ... the indicated causes ... the excretion of sodium ... urine #Algorithm #nephrology
Hyponatremia - Differential Algorithm Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP Hypotonic Hyponatremia: • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
Hyponatremia - Differential ... Cirrhosis, Nephrotic Syndrome ... Algorithm #diagnosis #causes ... #nephrology #sodium ... #low
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Dehydration - Loss of sodium ... conditions - Neurogenic ... heat illness → Hypernatremia ... - Metabolic acidosis ... consciousness, Coma/seizure
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... exertion/training - Seizures ... Hyperuricemia • Hyponatremia ... Isotonic fluid/Lactated ... #treatment #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... alkalosis • Normal or low ... Renal tubular acidosis ... tachycardia • Seizures ... #diagnosis #nephrology
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