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management tuberculosis differential latenttb active antigbm basement bronchiectasis criteria disease giomeruiar goodpastures hivaids idsa immune induration infectiousdiseases inflammatory interpretation iris
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
infection • Pulmonary ... Active TB: • ... : Active TB: • ... #Diagnosis #Management ... #Treatment #ActiveTB
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
infection • Pulmonary ... Active TB: • ... : Active TB: • ... #Diagnosis #Management ... #Treatment #ActiveTB
Tuberculosis Testing LATENT TB • LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
Testing LATENT TB ... • LTBI is diagnosed ... infection in patients ... IGRA/QuantiFERON-TB ... used to exclude pulmonary
Tuberculin Skin Test Interpretation - Threshold for treatment Induration cutoff >5mm: • Recent exposure to an individual
Tuberculin Skin Test ... Threshold for treatment ... individual with active ... TB • Abnormal ... #diagnosis #Interpretation
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS Treating LTBI (to prevent TB disease) Indications:
(+) screening test ... no evidence of active ... of screening test ... , select anti-TB ... and molecular diagnostic
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
: TB, NTM, PNA ... parenchyma Diagnosis ... function tests: ... mycobacteria Treatment ... #differential #diagnosis
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis) Anti-basement ... ANCA antibody, Anti-GBM ... ) Other tests: ... confirm DAH, r/o infection ... #management #treatment
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
(<100), except TB ... , pulmonary infiltrates ... lymphadenitis, pulmonary ... , hypoxia, and pulmonary ... • Persistently active
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
levels • NMO-IgG (anti-AQP4 ... negative, MOG-IgG test ... , Hep A/B/CMV, TB ... AntiCRMP IgG, Anti-Hu ... Transverse Myelitis Treatment
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
hemorrhage Diagnosis ... kidney biopsy Treatment ... sessions to clear active ... -3 weeks By Tess ... #nephrology #pulmonary
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