36 results
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Coagulation Tests ... #Algorithm #Coagulation ... #Abnormal #APTT ... #Laboratory #Hematology ... #Diagnosis #Workup
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Prolonged PTT, Normal ... Prolonged PTT, Normal ... #Differential #Diagnosis ... Algorithm #Causes #Hematology ... #coagulation #disorders
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
- Differential Diagnosis ... Destruction • Abnormal ... • Vasculitis Coagulation ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
Intravascular Coagulation ... consumption of coagulation ... Intravascular #Coagulation ... ISTH #Scoring #diagnosis ... #hematology #laboratory
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
an inhibitor of normal ... to have 50% of normal ... Mixing #Study #diagnosis ... #hematology #pathophysiology ... #hematology #laboratory
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... - APTT < 1.5 x normal ... #diagnosis #causes ... #treatment #management ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Decreased Support Of Dermal ... #Differential #Diagnosis ... #hematology #rheumatology ... #nonpalpable #dermatology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... #Coagulation #Cascade ... clot #PT #PTT #diagnosis ... #models #hematology ... #pathophysiology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... and Management ... hemosiderin • PT/aPTT normal ... #Management #Algorithm ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... marrow) -dys- (abnormal ... acute leukemia Management ... #Management #treatment ... #hematology #oncology