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diagnosis hematology management approach causes cell chronic cll differential erythematosus hodgkins leukemia lupus lymphocytic lymphoma mds myelodysplasia myelodysplastic plasmacytoma rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... syndrome (MDS) (normal ... anemia) Labs ... #Anemia #oncology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... RBC Production - Normal ... Deficiency • Aplastic ... #Classification ... Differential #Diagnosis #Algorithm
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... • Aplastic Anemia ... blood cells appear normal ... Workup: • Complete ... diagnosis #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
CLL Labs: 1. ... • Neutropenia, anemia ... Pure red cell aplasia ... Leukemia #diagnosis #workup ... #oncology #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
sedimentation rate + Normal ... Skin Disease Classification ... Cytopenias • Cardiac valve ... lymphopenia, low PLT • Anemia ... flares • CRP normal
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... products that define normal ... Hodgkin Lymphoma Workup ... #hematology #oncology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
-70 y/o • 2/3 Males ... mainly in the oral ... • No CRAB - no anemia ... #Plasmacytoma #Oncology ... #Diagnosis #Workup
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