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causes lfts cholangitis erythematosus gap globulin hypertension injury interpretation liverenzymes lupus management pbc protein proteingap rvalue sjogrens sle systemic transaminitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Diagnosis Algorithm ... US — Normal Bile ... • Alcoholic hepatitis ... Others #LFTs #Hepatology ... #Diagnosis #Algorithm
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Diagnosis Portal ... Clues to non-cirrhotic ... /acute hepatitis ... biliary cirrhosis ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Diagnosis Algorithm ... - If both are normal ... #injury #hepatitis ... diagnosis #algorithm ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... • ALT & AST normal ... • Bilirubin - Normal ... Viral hepatitis, ... #workup #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Check Acute viral hepatitis ... Check Acute viral hepatitis ... • Near normal ... #chemistry #diagnosis ... Hepatology #transaminitis
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
• Autoimmune hepatitis ... , primary biliary ... cirrhosis: 3%-20% ... Pharmacologic: • Severe oral ... #Rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
sedimentation rate + Normal ... Noninfectious hepatitis ... folds • Painless oral ... flares • CRP normal ... #Rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
HBV, EBV, VZV, hepatitis ... disease: Cirrhosis ... gastric tumors • Hematology ... light chain • Normal ... #diagnosis #hematology
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